How do we increase EPCs?

All of us, even adults, release IGF-1, a precursor to GH while we sleep. Its purpose is to stimulate a Th1 (immune response) in the gut to kill off accumulated toxins in the intestinal tract from a hard day’s work (especially necessary for those with poor HCl) and do other things associated with tissue repair like increase EPCs. The BEST way to stimulate IGF-1 production is to get a good night’s sleep!* NEVER take GH or GH stimulating hormones as they can stimulate cancer growth.*

There are nutritional protocols that increase EPCs which include Resveratrol, Green Tea Extract (EGCGs), and products that increase Nitric Oxide: Omega-3 fatty acids, Garlic, ALA, NAC, Hawthorne, Pomegranate, gamma and delta Tocopherols, Tocotrienols, Vitamin C, Vitamin D, Vitamin K2-MK7, the B Vitamins, Flavonoids, CoQ-10, L-Arginine, Citrulline, Carnitine, Taurine, Celery, Pycnogenol, Grape Seed Extract, Hesperidin, Melatonin, NADH, Selenium, Bilberry, Turmeric, Quercetin, cruciferous vegetables, and Medicinal Mushrooms – just to name a few.

Perhaps the greatest way to increase EPCs is through exercise.* The best choice of exercise is NOT sustained distance as in running five miles. To increase EPC production and protect yourself from BBB disruption, interval training is what you want to do – repetitions of 100% effort for a relatively short period of time followed by a repetition of 50% effort.*

Of course, you MUST eliminate the things that decrease EPCs which includes the removing the source of inflammation and addressing the three responses I’ve covered – oxidative stress, inflammation, and autoimmune disorders.

Lyme and Healing the Blood Brain Barrier

Protective Measures that Heal the Blood-Brain Barrier (BBB)

The following is a list of several OTHER things that everyone can do to protect against BBB disruption and heal the damage that already occurred. By “other” I mean that I am assuming that you are already correcting the CAUSE of endothelial damage that caused the astrocyte destruction. If you don’t fix the LYME, then forget about getting better!

Increase Endothelial Progenitor Cells (EPCs) – EPCs are similar to stem cells to your arteries. They rebuild and repair your tissue and need to be in high levels for regular, daily damage to be taken care of.* Measuring them (lab test) is perhaps the greatest indicator of early impairment – low values equaling a greater risk. They are created in the cord blood and bone marrow similar to stem cells and are released and mobilized when vascular damage occurs. Think of EPCs as little carriers of MnSOD and Glutathione – two mighty anti-inflammatory chemicals that stimulate healing.

Dr. Joseph A. Murphy

Clinic Director



Acute Phase

The borrelia bacteria is still in the blood stream or interstitial spaces. It can still be killed through the use of an antibiotic.*


Chronic Phase

The second one tiny bacterium enters inside a cell (goes intracellular), the patient has moved to the Chronic Phase (Phase 2) and antibiotics, unless long-term, are not effective. Lab tests to detect Lyme are now going to prove difficult as well.


Autoimmune Lyme Phase

Once the patient's immune system (Th2/B-cells) start creating antibodies to self-tissue, the patient has moved into the autoimmune phase (Phase 3). Natural immune stimulants such as Cats Claw, Echinacea, Garlic, and Vitamin C will simply assist the body to kill self-tissue and should be completely restricted!*

*Results may vary by patient and treatment.

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© 2018 Newport Mesa Wellness is a clinic in Newport Beach, CA offering functional medicine treatments for Lyme disease, autoimmune diseases, and cancer. | *Results may vary by patient and treatment.